17-HDHA

CAT: 0804-HY-113512-01Size: 25 μg (290.28 μM x 250 μL in Ethanol)Dry Ice: NoHazardous: No
CAT#:0804-HY-113512-01Size:25 μg (290.28 μM x 250 μL in Ethanol)
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Description
17-HDHA is a DHA-derived specialized proresolving mediator (SPM) . 17-HDHA enhances the antibody-mediated immune response against influenza virus. 17-HDHA enhances the differentiation of B cells toward the CD27+ CD38+ antibody-secreting cell phenotype, thereby strongly increasing IgM and IgG production by activated B cells[1][2].
CAS Number
[90780-52-2]
UNSPSC
12352211
Hazard Statement
H225, H319
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/17-hdha.html
Concentration
290.28 μM * 500 μL in Ethanol
Purity
98.8
Solubility
10 mM in DMSO
Smiles
CC/C=C\CC(O)/C=C/C=C\C/C=C\C/C=C\C/C=C\CCC(O)=O
Molecular Formula
C22H32O3
Molecular Weight
344.49
Precautions
H225, H319
References & Citations
[1]Ramon S, et al. The specialized proresolving mediator 17-HDHA enhances the antibody-mediated immune response against influenza virus: a new class of adjuvant? J Immunol. 2014 Dec 15;193 (12) :6031-40.|[2]Ramon S, et al. Specialized proresolving mediators enhance human B cell differentiation to antibody-secreting cells. J Immunol. 2012 Jul 15;189 (2) :1036-42.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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