KF-14124

• Description :

  KF-14124, an orally active organic nitrate, a long-acting vasodilator with highly selective venous dilating action. KF-14124 is used in the study for angina pectoris. KF-14124 shows good oral inhibition of lysine-vasopressin induced coronary vasospasm with a potency[1][2].

• CAS Number :

  [134186-26-8]

• UNSPSC :

  12352005

• Target :

  Others

• Type :

  Reference compound

• Related Pathways :

  Others

• Field of Research :

  Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/kf-14124.html

• Smiles :

  O=[N+]([O-])O[C@@H]1[C@](OC[C@@H]2N3CCN(CCCSC4=CC=CC=C4)CC3)([H])[C@]2([H])OC1

• Molecular Formula :

  C19H27N3O5S

• Molecular Weight :

  409.50

• References & Citations :

  [1]1,4:3,6-Dianhydrohexitol nitrate derivatives. I. Synthesis and antianginal activity of alkylpiperazine derivatives. Chem Pharm Bull (Tokyo) . 1993 Jun;41 (6) :1091-9.|[2]Giorgio Bertolini, et al. Overview: Recent Advances in Organic Nitrates. Current Opinion on Therapeutic Patents Volume 3, 1993 - Issue 10.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported