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KF-52

CAT: 0013-GTR19249697-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19249697-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
KF-52 is a potent small molecule inhibitor of phosphofructokinase-1 (PFK1) with an IC50 of 2.1 μM. It shifts cellular metabolism towards oxidative phosphorylation, as evidenced by an increased OCR/ECAR ratio, making it a useful tool for studying glycolysis and metabolic reprogramming in cancer and other diseases in vitro.
Field of Research
Metabolism Research
Smiles
C1CN ([C@@H] (C2=C1C3=CC=CC=C3N2) C (F) (F) F) C (=O) [C@@H]4[C@H]5C[C@@H] ([C@@H]4C (=O) O) C=C5
Molecular Formula
C21H19F3N2O3
Molecular Weight
404.382
Storage Conditions
-20°C
Notes
For research use only.

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