KF 22678

• Description :

  KF 22678 is a thioester derivative of leinamycin. KF 22678 exhibits a broad antitumor spectrum against human carcinoma xenografts, including lung, colon, ovary, and prostate cancers. KF 22678 can be used for the study of cancer[1].

• CAS Number :

  [186643-40-3]

• UNSPSC :

  12352005

• Target :

  Drug Derivative

• Related Pathways :

  Others

• Field of Research :

  Cancer

• Smiles :

  CC1=C(OC(O1)=O)CSC([C@](O)([C@@]2(C3)S(N([C@@H](C4=NC(/C=C\C=C\C([C@H](O[C@]5([H])CCCCO5)/C=C(C)\CC2)=O)=CS4)C)C3=O)=O)C)=O

• Molecular Formula :

  C32H38N2O10S3

• Molecular Weight :

  706.85

• References & Citations :

  [1]Ashizawa T, et al. Antitumor activity of KF22678, a novel thioester derivative of leinamycin. Anticancer Drugs. 1999 Oct;10 (9) :829-36.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported