DC-TEADin02

• Description :

  DC-TEADin02 is a potent TEAD autopalmitoylation inhibitor. DC-TEADin02 has TEAD autopalmitoylation inhibitory with the IC50 value of 197 nM. DC-TEADin02 can be used for the research of development, regeneration and tissue homeostasis[1].

• UNSPSC :

  12352005

• Target :

  YAP

• Type :

  Reference compound

• Related Pathways :

  Stem Cell/Wnt

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/dc-teadin02.html

• Purity :

  98.45

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  C=CS(=O)(NC1=CC=C(CC2=CC=C3C=CC=CC3=C2)C=C1)=O

• Molecular Formula :

  C19H17NO2S

• Molecular Weight :

  323.41

• References & Citations :

  [1]Wenchao Lu, et al. Discovery and biological evaluation of vinylsulfonamide derivatives as highly potent, covalent TEAD autopalmitoylation inhibitors. Eur J Med Chem. 2019 Dec 15;184:111767.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2380228-45-3]