DC-TEADin02

• UNSPSC Description:

  DC-TEADin02 is a potent TEAD autopalmitoylation inhibitor. DC-TEADin02 has TEAD autopalmitoylation inhibitory with the IC50 value of 197 nM. DC-TEADin02 can be used for the research of development, regeneration and tissue homeostasis[1].

• Target Antigen:

  YAP

• Type:

  Reference compound

• Related Pathways:

  Stem Cell/Wnt

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/dc-teadin02.html

• Purity:

  98.00

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  C=CS(=O)(NC1=CC=C(CC2=CC=C3C=CC=CC3=C2)C=C1)=O

• Molecular Weight:

  323.41

• References & Citations:

  [1]Wenchao Lu, et al. Discovery and biological evaluation of vinylsulfonamide derivatives as highly potent, covalent TEAD autopalmitoylation inhibitors. Eur J Med Chem. 2019 Dec 15;184:111767.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Clinical Information:

  No Development Reported

• CAS Number:

  2380228-45-3