Products for Research Use Only

DC-TEADin02

CAT: 0804-HY-126621-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-126621-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DC-TEADin02 is a potent TEAD autopalmitoylation inhibitor. DC-TEADin02 has TEAD autopalmitoylation inhibitory with the IC50 value of 197 nM. DC-TEADin02 can be used for the research of development, regeneration and tissue homeostasis[1].
CAS Number
2380228-45-3
UNSPSC
12352005
Target
YAP
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dc-teadin02.html
Purity
98.45
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C=CS(=O)(NC1=CC=C(CC2=CC=C3C=CC=CC3=C2)C=C1)=O
Molecular Formula
C19H17NO2S
Molecular Weight
323.41
References & Citations
[1]Wenchao Lu, et al. Discovery and biological evaluation of vinylsulfonamide derivatives as highly potent, covalent TEAD autopalmitoylation inhibitors. Eur J Med Chem. 2019 Dec 15;184:111767.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported