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Dronedarone Hydrochloride

CAT: 0572-TRC-D679445-50MGSize: 50 mgDry Ice: NoHazardous: No
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CAT#:0572-TRC-D679445-50MGSize:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
141625-93-6
Synonyms
Methanesulfonamide, N-[2-butyl-3-[4-[3-(dibutylamino)propoxy]benzoyl]-5-benzofuranyl]-, hydrochloride (1:1); Methanesulfonamide, N-[2-butyl-3-[4-[3-(dibutylamino)propoxy]benzoyl]-5-benzofuranyl]-, monohydrochloride (9CI); Dronedarone hydrochloride; Multaq
Hazard Statement
Harmful if swallowed.
Purity
>95% (HPLC)
Smiles
Cl.CCCCN(CCCC)CCCOc1ccc(cc1)C(=O)c2c(CCCC)oc3ccc(NS(=O)(=O)C)cc23
Molecular Formula
C31 H44 N2 O5 S . Cl H
Molecular Weight
593.22
InChI
InChI=1S/C31H44N2O5S.ClH/c1-5-8-12-29-30(27-23-25(32-39(4,35)36)15-18-28(27)38-29)31(34)24-13-16-26(17-14-24)37-22-11-21-33(19-9-6-2)20-10-7-3;/h13-18,23,32H,5-12,19-22H2,1-4H3;1H
Additionnal Information
IUPAC name: N-[2-butyl-3-[4-[3-(dibutylamino)propoxy]benzoyl]-1-benzofuran-5-yl]methanesulfonamide;hydrochloride
Shipping Conditions
Ice Packs
Storage Conditions
+4°C

Chemical Information

Dronedarone Hydrochloride

Dronedarone Hydrochloride is the hydrochloride salt form of dronedarone, an orally bioavailable benzofuran derivative, with anti-arrhythmic activity. Upon oral administration, and although the exact mechanism of action through which dronedarone exerts its anti-arrhythmic effect has not been fully elucidated, it inhibits multiple voltage-gated ion channels, including sodium, potassium, and calcium ion channels, and restores the normal sinus rhythm and reduces heart rate in atrial fibrillation. It also non-competitively antagonizes adrenergic receptors.

CAS Number141625-93-6
PubChem CID219025
IUPAC NameN-[2-butyl-3-[4-[3-(dibutylamino)propoxy]benzoyl]-1-benzofuran-5-yl]methanesulfonamide;hydrochloride
Molecular FormulaC31H45ClN2O5S
Molecular Weight593.2
Topological Polar Surface Area97.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count7
Rotatable Bond Count18
Heavy Atom Count40
Formal Charge0
Complexity800
SMILES
CCCCC1=C(C2=C(O1)C=CC(=C2)NS(=O)(=O)C)C(=O)C3=CC=C(C=C3)OCCCN(CCCC)CCCC.Cl
InChI
InChI=1S/C31H44N2O5S.ClH/c1-5-8-12-29-30(27-23-25(32-39(4,35)36)15-18-28(27)38-29)31(34)24-13-16-26(17-14-24)37-22-11-21-33(19-9-6-2)20-10-7-3;/h13-18,23,32H,5-12,19-22H2,1-4H3;1H
InChIKey
DWKVCQXJYURSIQ-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Dronedarone Hydrochloride
CAS: 141625-93-6
CID: 219025
Formula: C31H45ClN2O5S
MW: 593.2
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight593.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count7
Rotatable Bond Count18
Exact Mass592.2737714
Monoisotopic Mass592.2737714
Topological Polar Surface Area97.2 Ų
Heavy Atom Count40
Formal Charge0
Complexity800
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
FD22615Dronedarone hydrochloride
HY-75839-01Dronedarone (Hydrochloride)
HY-A0016SDronedarone-d6 (hydrochloride)
CS-O-03206Dronedarone-d6 Hydrochloride
HY-75839R-01Dronedarone (Hydrochloride) (Standard)
A11389-200Dronedarone Hydrochloride 200mg
A11389-50Dronedarone Hydrochloride 50mg
A11389-10Dronedarone Hydrochloride 10mg
AR-D02429-01Dronedarone Hydrochloride Impurity A
FD21148-01Desbutyl dronedarone hydrochloride

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