ASK1-IN-1
CAT:
804-HY-133554-01
Size:
50 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
ASK1-IN-1
- CAS Number: 2411382-24-4
- UNSPSC Description: ASK1-IN-1 is a CNS-penetrant ASK1 (apoptosis signal-regulating kinase 1) inhibitor, with good potency (cell IC50=138 nM; Biochemical IC50=21 nM)[1].
- Target Antigen: MAP3K; p38 MAPK
- Type: Reference compound
- Related Pathways: MAPK/ERK Pathway
- Field of Research: Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/ask1-in-1-1.html
- Smiles: COC1=NN(C2=NC=CN=C2)C=C1C(NC3=NC(C4=NN=CN4C(C)C)=CC=C3)=O
- Molecular Weight: 405.41
- References & Citations: [1]Xin Z, et al. Discovery of CNS-Penetrant Apoptosis Signal-Regulating Kinase 1 (ASK1) Inhibitors. ACS Med Chem Lett. 2020;11(4):485-490. Published 2020 Feb 12.
- Shipping Conditions: Room Temperature