UC-112
CAT:
804-HY-12842-03
Size:
50 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
UC-112
- CAS Number: 383392-66-3
- UNSPSC Description: UC-112 is a new and highly effective inhibitor of apoptosis inhibitory protein IAP, with an IC50 value of 0.7-3.4uM in cancer cells.
- Target Antigen: Apoptosis; IAP
- Type: Reference compound
- Related Pathways: Apoptosis
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/UC-112.html
- Purity: 98.92
- Solubility: DMSO : 33.33 mg/mL (ultrasonic)
- Smiles: OC1=C2N=CC=CC2=C(COCC3=CC=CC=C3)C=C1CN4CCCC4
- Molecular Weight: 348.44
- References & Citations: [1]Wang J, et al. Discovery of novel second mitochondria-derived activator of caspase mimetics as selective inhibitor of apoptosis protein inhibitors. J Pharmacol Exp Ther. 2014 May;349(2):319-29.|[2]Qinghui Wang, et al. Synthesis and biological evaluation of indole-based UC-112 analogs as potent and selective survivin inhibitors. Eur J Med Chem
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported