Products for Research Use Only
RegisterLogin

UC-764864

CAT: 0804-HY-153775-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-153775-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
UC-764864 is a UBE2N inhibitor. UC-764864 inhibits UBE2N enzymatic activity. UC-764864 has cytotoxic effects and inhibition of UBE2N-dependent signaling in leukemic cells. UC-764864 blocks ubiquitination of innate immune- and inflammatory-related substrates in human AML cell lines[1].
CAS Number
278806-03-4
UNSPSC
12352005
Target
E1/E2/E3 Enzyme
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/uc-764864.html
Concentration
10mM
Purity
99.85
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=C(CC)C=C1)/C=C/SC2=NC3=C(N2)C=CC(C)=C3
Molecular Formula
C19H18N2OS
Molecular Weight
322.42
References & Citations
[1]Barreyro L, et al. Blocking UBE2N abrogates oncogenic immune signaling in acute myeloid leukemia. Sci Transl Med. 2022 Mar 9;14 (635) :eabb7695.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-124514UC-857993
HY-105491UC-38
HY-12842-01UC-112
HY-122685UC-773587
HY-15351UC-781
HY-114266-01UC-1728
HY-120395-01UC-514321
HY-105489UC-84
HY-147215UC-1V150
HY-117001CB-7646

Alternative Products

CatalogName
MBS5820795UC-764864
BA7689-100UC-1728
T13950-01UC-514321
257010-01UC 112
T29037-01UC-781
MBS3604632-01UC-857993
MBS3600570-01UC-773587
MBS5803820UC-1V150
GTR19231831UC-764865
GTR19202955-01UC-112

Popular Products