UC-1V150
CAT:
804-HY-147215
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
UC-1V150
- CAS Number: 927822-45-5
- UNSPSC Description: UC-1V150 is a specific TLR7 (Toll-like receptor) agonist that stimulates cellular immune responses and has anti-tumor activity. UC-1V150 can be used to synthesize ISAC (Immune-Stimulating Antibody Conjugates) molecule[1][2].
- Target Antigen: Toll-like Receptor (TLR)
- Type: Reference compound
- Related Pathways: Immunology/Inflammation
- Applications: COVID-19-immunoregulation
- Field of Research: Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/uc-1v150.html
- Solubility: 10 mM in DMSO
- Smiles: O=CC1=CC=C(CN2C(NC3=C2N=C(OCCOC)N=C3N)=O)C=C1
- Molecular Weight: 343.34
- References & Citations: [1]Christina C N Wu, et al. Immunotherapeutic activity of a conjugate of a Toll-like receptor 7 ligand. Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):3990-5.|[2]L N Dahal, et al. UC-1V150, a potent TLR7 agonist capable of activating macrophages and potentiating mAb-mediated target cell deletion. Scand J Immunol. 2018 Jun;87(6):e12666.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported