BMS-457

• Description:

  BMS-457 is a potent and selective CCR1 antagonist. BMS-457 can be used in the study of rheumatoid arthritis[1].

• UNSPSC:

  12352101

• Target:

  CCR

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Immunology/Inflammation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/bms-457.html

• Smiles:

  O[C@@]1(C2=CC=C(C=C2)Cl)C(C)(CN(CC1)C([C@@H](C(C)C)NC([C@@H]3CC[C@H](C3)O)=O)=O)C

• Molecular Formula:

  C24H35ClN2O4

• Molecular Weight:

  451.00

• References & Citations:

  [1]Gardner DS, et al. The discovery of BMS-457, a potent and selective CCR1 antagonist. Bioorg Med Chem Lett. 2013 Jul 1;23 (13) :3833-40.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [946594-19-0]