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AChE-IN-73

CAT: 0804-HY-163980Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-163980Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AChE-IN-73 (compound 6) is an insecticide with higher toxicity than HY-B0815. The LC50 for C. pipiens is 78.0 mg/L. AChE-IN-73 has high affinity for acetylcholinesterase (AChE) and nicotinic acetylcholine receptors (nAChR), with binding energies of -8.11 kcal/mol and -6.27 kcal/mol, respectively. AChE-IN-73 is a potentially potent mosquito inhibitor[1].
UNSPSC
12352005
Target
Cholinesterase (ChE) ; nAChR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ache-in-73.html
Smiles
N#CC1=C(/N=C/NCC2=CC=CO2)OC3=C(C=CC4=CC=CC=C43)C1C5=CC=CC=C5Cl
Molecular Formula
C26H18ClN3O2
Molecular Weight
439.89
References & Citations
[1]Synthesis, molecular modelling and evaluation of larvicidal efficacy of annulated Benzo[h]chromenes against Culex pipiens L. Larvae
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported