MHY-1685

• Description :

  MHY-1685, a novel mammalian target of rapamycin (mTOR) inhibitor, provides opportunities to improve hCSC-based myocardial regeneration.

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H312, H332

• Target :

  MTOR

• Type :

  Reference compound

• Related Pathways :

  PI3K/Akt/mTOR

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/mhy-1685.html

• Concentration :

  10mM

• Purity :

  99.84

• Solubility :

  DMSO : 62.5 mg/mL (ultrasonic)

• Smiles :

  O=C(NC(NC/1=O)=O)C1=C/C2=CC=C(O)C=C2

• Molecular Formula :

  C11H8N2O4

• Molecular Weight :

  232.19

• Precautions :

  H302, H312, H332

• References & Citations :

  [1]Park JH, et al. Human cardiac stem cells rejuvenated by modulating autophagy with MHY-1685 enhance the therapeutic potential for cardiac repair. Exp Mol Med. 2021 Sep;53 (9) :1423-1436.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [27406-31-1]