MHY 553

CAT: 0804-HY-128135-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-128135-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MHY 553 is a PPARĪ± agonist that is effective when taken orally. MHY 553 helps alleviate liver fat accumulation by increasing fatty acid oxidation and reducing inflammation during the aging process. MHY 553 inhibits the accumulation of triglycerides induced by liver X receptor agonists in HepG2 cells. MHY 553 significantly suppresses the expression of inflammatory mRNA in aging rats[1].
CAS Number
[6265-56-1]
UNSPSC
12352005
Target
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/mhy-553.html
Smiles
OC1=CC=C(C2=NC3=CC=CC=C3S2)C(O)=C1
Molecular Formula
C13H9NO2S
Molecular Weight
243.28
References & Citations
[1]Seong Min Kim, et al. Novel PPARĪ± agonist MHY553 alleviates hepatic steatosis by increasing fatty acid oxidation and decreasing inflammation during aging. Oncotarget. 2017 May 8;8 (28) :46273ā€“46285.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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