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NW-1689

CAT: 0804-HY-W269511-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W269511-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NW-1689 is a process-related impurity of safinamide mesilate (SAFM) . SAFM is a drug used to treat Parkinson's disease (PD) . It is a highly selective and reversible inhibitor of monoamine oxidase-B (MAO-B) and also blocks sodium channels and N-type calcium channels. These effects of SAFM help reduce the breakdown of dopamine and inhibit the release of glutamate. NW-1689 has a similar chemical structure to SAFM and has some similar pharmacological effects as SAFM, and can be used in Parkinson's disease research[1].
CAS Number
405-85-6
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Drug Derivative
Type
Reference compound
Related Pathways
Others
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/nw-1689.html
Smiles
C1=CC(=CC(=C1)F)COC2=CC=C(C=C2)C(=O)O
Molecular Formula
C14H11FO3
Molecular Weight
246.23
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Zou L, et al. Identification, characterization, and quantification of impurities of safinamide mesilate: process-related impurities and degradation products[J]. Journal of AOAC International, 2017, 100 (4) : 1029-1037.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported