Ru-TRZ2

• Description:

  Ru-TRZ2 is a potent ruthenium-based chemotherapeutic agent. Ru-TRZ2 induces apoptosis and necroptosis. Ru-TRZ2 shows antitumor activity[1].

• UNSPSC:

  12352211

• Target:

  Apoptosis; Necroptosis

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/ru-trz2.html

• Smiles:

  FC(F)(F)S(=O)([O-])=O.CN(C(CCC)=O)/N=N/C1=CC=C(C#[N][Ru+2]2([])[P](C3=CC=CC=C3)(C4=CC=CC=C4)CC[P]2(C5=CC=CC=C5)C6=CC=CC=C6)C=C1.FC(F)(F)S(=O)([O-])=O.C7CCCC7

• Molecular Formula:

  C45H43F6N4O7P2RuS2

• Molecular Weight:

  1092.98

• References & Citations:

  [1]Gonçalves J, et al. Necroptosis induced by ruthenium (II) complexes as mitochondrial disruptors. Cell Death Discov. 2024 May 28;10 (1) :261.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported