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RU Phosphoramidite

CAT: 0804-HY-W048482-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0804-HY-W048482-01Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
CAS Number
118362-03-1
Product Name Alternative
DMT-2'O-TBDMS-rU phosphoramidite
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ru-phosphoramidite.html
Purity
99.22
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(NC(C=C1)=O)N1[C@@H]([C@H](O[Si](C)(C)C(C)(C)C)[C@@H]2OP(N(C(C)C)C(C)C)OCCC#N)O[C@@H]2COC(C3=CC=C(OC)C=C3)(C4=CC=C(OC)C=C4)C5=CC=CC=C5
Molecular Formula
C45H61N4O9PSi
Molecular Weight
861.05
Precautions
H302, H315, H319
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

rU Phosphoramidite
CAS Number118362-03-1
PubChem CID10898199
IUPAC Name3-[[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[tert-butyl(dimethyl)silyl]oxy-5-(2,4-dioxopyrimidin-1-yl)oxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
Molecular FormulaC45H61N4O9PSi
Molecular Weight861.0
Topological Polar Surface Area141
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count11
Rotatable Bond Count20
Heavy Atom Count60
Formal Charge0
Complexity1430
SMILES
CC(C)N(C(C)C)P(OCCC#N)O[C@@H]1[C@H](O[C@H]([C@@H]1O[Si](C)(C)C(C)(C)C)N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC
InChI
InChI=1S/C45H61N4O9PSi/c1-31(2)49(32(3)4)59(55-29-15-27-46)57-40-38(56-42(48-28-26-39(50)47-43(48)51)41(40)58-60(10,11)44(5,6)7)30-54-45(33-16-13-12-14-17-33,34-18-22-36(52-8)23-19-34)35-20-24-37(53-9)25-21-35/h12-14,16-26,28,31-32,38,40-42H,15,29-30H2,1-11H3,(H,47,50,51)/t38-,40-,41-,42-,59?/m1/s1
InChIKey
SKNLXHRBXYGJOC-ZMHKPELYSA-N
Chemical Structure
2D Structure
2D structure of rU Phosphoramidite
CAS: 118362-03-1
CID: 10898199
Formula: C45H61N4O9PSi
MW: 861.0
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight861.0
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count11
Rotatable Bond Count20
Exact Mass860.39454307
Monoisotopic Mass860.39454307
Topological Polar Surface Area141 Ų
Heavy Atom Count60
Formal Charge0
Complexity1430
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes