RU-505
CAT:
804-HY-117983
Size:
1 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
RU-505
- CAS Number: 1314206-29-5
- UNSPSC Description: RU-505 is an effective β-amyloid (Aβ)-fibrinogen interaction inhibitor with IC50s of 5.00 and 2.72 μM in fluorescence polarization (FP) and AlphaLISA assays, respectively. RU-505 is highly permeable to the BBB. RU-505 reduces cerebral amyloid angiopathy (CAA). RU-505 can be used for the research of Alzheimer’s disease (AD)[1].
- Target Antigen: Amyloid-β
- Type: Reference compound
- Related Pathways: Neuronal Signaling
- Applications: Neuroscience-Neurodegeneration
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/ru-505.html
- Solubility: 10 mM in DMSO
- Smiles: O=C(C1=NC2=CC(C(C)(C)C)=NN2C(C3=CC=C(F)C=C3)=C1)N(CCN(C)C)CC4=CC=CC=C4
- Molecular Weight: 473.58
- References & Citations: [1]Hyung Jin Ahn, et al. A novel Aβ-fibrinogen interaction inhibitor rescues altered thrombosis and cognitive decline in Alzheimer's disease mice. J Exp Med. 2014 Jun 2;211(6):1049-62.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported