Pomalidomide-C2-acid

• Description :

  Pomalidomide-C2-acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H361

• Target :

  E3 Ligase Ligand-Linker Conjugates

• Type :

  Reference compound

• Related Pathways :

  PROTAC

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/pomalidomide-c2-acid.html

• Purity :

  99.78

• Solubility :

  DMSO : 50 mg/mL (ultrasonic)

• Smiles :

  O=C(CCNC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O)O

• Molecular Formula :

  C16H15N3O6

• Molecular Weight :

  345.31

• Precautions :

  H361

• References & Citations :

  [1]Md Kabir, et al. Discovery and Characterization of a Novel Cereblon-Recruiting PRC1 Bridged PROTAC Degrader. J Med Chem. 2024 Apr 25;67 (8) :6880-6892.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  Cereblon

• CAS Number :

  [2225940-46-3]