Pomalidomide-C2-Br

• Description:

  Pomalidomide-C2-Br is an E3 Ligase Ligand (HY-14658) and linker (HY-W007731) conjugate. Pomalidomide-C2-Br can be used to synthesize PROTAC AR Degrader-8 (HY-170329) [1].

• UNSPSC:

  12352005

• Target:

  E3 Ligase Ligand-Linker Conjugates

• Related Pathways:

  PROTAC

• Field of Research:

  Cancer

• Smiles:

  O=C1NC(C(CC1)N2C(C3=C(C2=O)C(NCCBr)=CC=C3)=O)=O

• Molecular Formula:

  C15H14BrN3O4

• Molecular Weight:

  380.19

• References & Citations:

  [1]Ha S, et al. Discovery of a highly potent, N-terminal domain-targeting degrader of AR-FL/AR-V7 for the treatment of prostate cancer. Eur J Med Chem. 2025 Jan 15;282:117079.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2940940-74-7]