Pomalidomide-PEG6-C2-COOH

• Description:

  Pomalidomide-PEG6-C2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide (HY-10984) based cereblon ligand and 6-unit PEG linker used in PROTAC technology[1].

• Product Name Alternative:

  Pomalidomide-PEG6-COOH

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  E3 Ligase Ligand-Linker Conjugates

• Related Pathways:

  PROTAC

• Field of Research:

  Cancer

• Purity:

  98.95

• Smiles:

  O=C(CCOCCOCCOCCOCCOCCOCCNC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O)O

• Molecular Formula:

  C28H39N3O12

• Molecular Weight:

  609.62

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Qiu X, et al. Jiang B. Chemoselective Synthesis of Lenalidomide-Based PROTAC Library Using Alkylation Reaction. Org Lett. 2019;21 (10) :3838-3841.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound2

• Clinical Information:

  No Development Reported

• CAS Number:

  [2225148-49-0]