Tempol

• Description :

  Tempol is a general superoxide dismutase (SOD) -mimetic agent that efficiently neutralizes reactive oxygen species (ROS) .

• Product Name Alternative :

  4-Hydroxy-TEMPO

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H318, H402

• Target :

  Autophagy; Reactive Oxygen Species (ROS)

• Type :

  Reference compound

• Related Pathways :

  Autophagy; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/Tempol.html

• Purity :

  99.78

• Solubility :

  H2O : 5.56 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles :

  [O]N1C(C)(C)CC(O)CC1(C)C

• Molecular Formula :

  C9H18NO2

• Molecular Weight :

  172.24

• Precautions :

  H302, H318, H402

• References & Citations :

  [1]Vilar-Pereira G, et al. Resveratrol Reverses Functional Chagas Heart Disease in Mice. PLoS Pathog. 2016 Oct 27;12 (10) :e1005947.|[2]Chatterjee PK, et al. Tempol, a membrane-permeable radical scavenger, reduces oxidant stress-mediated renal dysfunction and injury in the rat. Kidney Int. 2000 Aug;58 (2) :658-73.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  Store at room temperature 3 years

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 3

• CAS Number :

  [2226-96-2]