Tempol

• UNSPSC Description:

  Tempol is a general superoxide dismutase (SOD)-mimetic agent that efficiently neutralizes reactive oxygen species (ROS).

• Target Antigen:

  Autophagy; Reactive Oxygen Species

• Type:

  Reference compound

• Related Pathways:

  Autophagy;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/Tempol.html

• Purity:

  99.73

• Solubility:

  H2O : 5.56 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  [O]N1C(C)(C)CC(O)CC1(C)C

• Molecular Weight:

  172.24

• References & Citations:

  [1]Vilar-Pereira G, et al. Resveratrol Reverses Functional Chagas Heart Disease in Mice. PLoS Pathog. 2016 Oct 27;12(10):e1005947.|[2]Chatterjee PK, et al. Tempol, a membrane-permeable radical scavenger, reduces oxidant stress-mediated renal dysfunction and injury in the rat. Kidney Int. 2000 Aug;58(2):658-73.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  Store at room temperature 3 years

• Clinical Information:

  Phase 3

• CAS Number:

  2226-96-2