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Tempone

CAT: 0804-HY-129242-01Size: 10 gDry Ice: NoHazardous: No
CAT#:0804-HY-129242-01Size:10 g
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tempone (4-Oxo-Tempo) is a stable water-soluble nitro radical. Tempone is widely used as a contrast agent for metabolic activity and hypoxic sensitivity in electron spin resonance spectroscopy, magnetic resonance imaging and dynamic nuclear polarization. Tempone reduces superoxide radicals by mimicking the activity of superoxide dismutase (SOD), thereby reducing the formation of hydroxyl radicals and peroxynitrites. Tempone can be used in the study of ischemia-reperfusion injury and acute renal failure[1].
CAS Number
[2896-70-0]
Product Name Alternative
4-Oxo-Tempo
UNSPSC
12352005
Hazard Statement
H302, H317, H372, H410
Target
SOD
Type
Reference compound
Related Pathways
Immunology/Inflammation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/tempone.html
Purity
99.10
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
[O]N1C(C)(C)CC(CC1(C)C)=O
Molecular Formula
C9H16NO2?
Molecular Weight
170.23
Precautions
H302, H317, H372, H410
References & Citations
[1]Patel N S A, et al. TEMPONE reduces renal dysfunction and injury mediated by oxidative stress of the rat kidney[J]. Free Radical Biology and Medicine, 2002, 33 (11) : 1575-1589.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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