ζ-Stat (trisodium)

CAT: 0804-HY-123979A-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-123979A-01Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
ζ-Stat trisodium (NSC37044 trisodium) is a specific and atypical PKC-ζ inhibitor, with an IC50 of 5 μM. ζ-Stat trisodium can reduce melanoma cell lines proliferation and induce apoptosis, and has antitumor activity in vitro[1][2].
CAS Number
[31894-34-5]
Product Name Alternative
NSC37044 (trisodium)
UNSPSC
12352005
Target
Apoptosis; PKC
Type
Reference compound
Related Pathways
Apoptosis; Epigenetics; TGF-beta/Smad
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ζ-stat-trisodium.html
Purity
97.0
Solubility
H2O : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=S(C1=C2C(O)=CC(S(=O)(O[Na])=O)=CC2=CC(S(=O)(O[Na])=O)=C1)(O[Na])=O
Molecular Formula
C10H5Na3O10S3
Molecular Weight
450.31
References & Citations
[1]Ratnayake WS, et, al. Oncogenic PKC-ι activates Vimentin during epithelial-mesenchymal transition in melanoma; a study based on PKC-ι and PKC-ζ specific inhibitors. Cell Adh Migr. 2018; 12 (5) :447-463.|[2]Islam SMA, et, al. Atypical Protein Kinase-C inhibitors exhibit a synergistic effect in facilitating DNA damaging effect of 5-fluorouracil in colorectal cancer cells. Biomed Pharmacother. 2020 Jan; 121:109665.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PKCζ

Related Products

CatalogName
HY-B0993-01Mangafodipir (trisodium)
HY-137697D-01DdCTP (trisodium)
HY-137611Aα, β-MTDP (trisodium)
HY-W250844A-01DO3A (trisodium)
HY-137607AUDP (trisodium)
HY-137682AGMPCP (trisodium)
HY-137717ACOPCP (trisodium)
HY-177726UTPU (trisodium)
HY-W017068-01DUTP (trisodium)
HY-134103A-01DdGTP (trisodium)

Alternative Products

CatalogName
bs-6783C-01ζ-Stat trisodium
MBS5785681-01zeta-Stat trisodium
BA2941-5ζ-Stat
BUP02320-01?-Stat
MBS3616748-01dUTP trisodium
MBS5820300ddTTP trisodium
MBS5756049Mangafodipir trisodium
sc-253801Trisodium trimetaphosphate
JH919227CALOXETATE TRISODIUM
3125611Trisodium Citrate

Popular Products