GMPCP (trisodium)

• Description :

  GMPCP (GpCp) trisodium (Compound 7 trisodium) is a guanosine derivative is a CD73 inhibitor, with Kis of 1110 nM (rat soluble CD73) and 410 nM (human soluble CD73) respectively. GMPCP (GpCp) trisodium can be used for research of cancer[1].

• Product Name Alternative :

  GpCp (trisodium)

• UNSPSC :

  12352005

• Target :

  CD73

• Related Pathways :

  Immunology/Inflammation

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Smiles :

  O[C@H]1[C@@H](O)[C@H](N2C=NC3=C2NC(N)=NC3=O)O[C@@H]1COP(CP(O[Na])(O[Na])=O)(O[Na])=O

• Molecular Formula :

  C11H14N5Na3O10P2

• Molecular Weight :

  507.17

• References & Citations :

  [1]Bhattarai S, et al. 2-Substituted α, β-Methylene-ADP Derivatives: Potent Competitive Ecto-5'-nucleotidase (CD73) Inhibitors with Variable Binding Modes. J Med Chem. 2020 Mar 26;63 (6) :2941-2957.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported