COPCP (trisodium)

• Description :

  COPCP trisodium (Compound 7a) is a potent and selective ecto-5'-nucleotidase CD73 inhibitor. COPCP trisodium blocks CD73-mediated adenosine production, reducing the inhibitory effect of adenosine on immune cells. COPCP trisodium is promising for research of cancers[1].

• UNSPSC :

  12352005

• Target :

  CD73

• Related Pathways :

  Immunology/Inflammation

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Smiles :

  O[C@@H]1[C@H](O)[C@@H](COP(CP(O[Na])(O[Na])=O)(O[Na])=O)O[C@H]1N2C=CC(N)=NC2=O

• Molecular Formula :

  C10H14N3Na3O10P2

• Molecular Weight :

  467.15

• References & Citations :

  [1]Junker A, et al. Structure-Activity Relationship of Purine and Pyrimidine Nucleotides as Ecto-5'-Nucleotidase (CD73) Inhibitors. J Med Chem. 2019 Apr 11;62 (7) :3677-3695.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported