α,β-MTDP (trisodium)

• UNSPSC Description:

  α,β-MTDP trisodium, a thymidylate analog, is a thymidine kinase inhibitor with a Ki of 23 µM[1].

• Target Antigen:

  DNA/RNA Synthesis

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/α-β-mtdp-trisodium.html

• Smiles:

  O[C@H]1C[C@@H](O[C@@H]1COP(CP(O[Na])(O[Na])=O)(O[Na])=O)N(C(N2)=O)C=C(C)C2=O

• Molecular Weight:

  466.16

• References & Citations:

  [1]H Toide, et al. Effect of thymidine and thymidylate analogs on nucleic acid synthesis in tumor cells. Gan. 1977 Apr;68(2):159-63.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  71370-60-0