UTPU (trisodium)

• Description:

  UTPU trisodium (Compound 19) is a selective P2Y6R agonist with an EC50 of 0.4 μM. UTPU trisodium can activate the intracellular calcium signaling pathway mediated by P2Y6. UTPU trisodium can be used for the research of inflammation[1].

• UNSPSC:

  12352005

• Target:

  P2Y Receptor

• Related Pathways:

  GPCR/G Protein

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Smiles:

  O=C(C=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(OP(OP(OC[C@H]3O[C@@H](N(C(N4)=O)C=CC4=O)[C@H](O)[C@@H]3O)(O[Na])=O)(O[Na])=O)(O[Na])=O)O2)NC1=O

• Molecular Formula:

  C18H22N4Na3O20P3

• Molecular Weight:

  776.27

• References & Citations:

  [1]Douglass JG, et al. Lipophilic modifications to dinucleoside polyphosphates and nucleotides that confer antagonist properties at the platelet P2Y12 receptor. J Med Chem. 2008 Feb 28;51 (4) :1007-25.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Oligonucleotides

• Clinical Information:

  No Development Reported

• Isoform:

  P2Y6 Receptor

• CAS Number:

  [401618-61-9]