NMDA

• Description:

  NMDA is a specific agonist for NMDA receptor mimicking the action of glutamate, the neurotransmitter which normally acts at that receptor.

• Product Name Alternative:

  N-Methyl-D-aspartic acid

• UNSPSC:

  12352211

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Endogenous Metabolite; iGluR

• Type:

  Natural Products

• Related Pathways:

  Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/NMDA.html

• Purity:

  99.73

• Solubility:

  DMSO : 10 mg/mL (ultrasonic) |H2O : 33.33 mg/mL (ultrasonic)

• Smiles:

  O=C(O)C[C@H](C(O)=O)NC

• Molecular Formula:

  C5H9NO4

• Molecular Weight:

  147.13

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Xia JD, et al. Centrally mediated ejaculatory response via sympathetic outflow in rats: role of N-methyl-D-aspartic acid receptors in paraventricular nucleus. Andrology. 2016 Nov 16.|[2]Yoneda Y, et al. Enhancement of [3H]glutamate binding by N-methyl-D-aspartic acid in rat adrenal. Brain Res. 1987 Mar 17;406 (1-2) :24-31.|[3]Jiang L, et al. Decrease of growth and differentiation factor 10 contributes to neuropathic pain through N-methyl-D-aspartate receptor activation. Neuroreport. 2017 May 24;28 (8) :444-450.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Natural Products

• Clinical Information:

  Phase 3

• Isoform:

  Human Endogenous Metabolite; NMDA Receptor

• CAS Number:

  [6384-92-5]