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NMDAR antagonist 4

CAT: 0804-HY-107705Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-107705Size:1 Each
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Description
NMDAR antagonist 4 (Compound 8) is the antagonist for NMDA receptor that binds NMDA receptor on glycine site with Ki >100 μM[1].
CAS Number
132623-44-0
UNSPSC
12352005
Target
IGluR
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
OC(C1=NC2=CC=CC=C2C=C1CC(O)=O)=O
Molecular Formula
C12H9NO4
Molecular Weight
231.20
References & Citations
[1]Lu T, et al., Valid and Convenient Questionnaire Assessment of Chinese Body Constitution: Item Characteristics, Reliability, and Construct Validation. Patient Prefer Adherence. 2022 Aug 2;16:1875-1884.|[2]Smith E C R, et al. Structure-activity relationships of a series of glycine antagonists related to 5, 7-dichlorokynurenic acid and 3- (2-carboxy-6-chloroindol-3-yl) acetic acid[J]. Bioorganic & Medicinal Chemistry Letters, 1993, 3 (1) : 81-84.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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