YT 146

• Description :

  YT 146 is a potent agonist of A2 adenosine receptor (A2 AR) agonist. YT 146 causes a concentreation dependent cAMP accumulation, with the EC50 of 1.5 nM. YT 146 has cardioprotective effects[1].

• UNSPSC :

  12352005

• Target :

  Adenosine Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein

• Field of Research :

  Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/yt-146.html

• Purity :

  99.72

• Smiles :

  O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N2C3=NC(C#CCCCCCC)=NC(N)=C3N=C2

• Molecular Formula :

  C18H25N5O4

• Molecular Weight :

  375.42

• References & Citations :

  [1]Jun Sasamori, et al. Cardioprotective effects of 2-octynyladenosine (YT-146) in ischemic/reperfused rat hearts. J Cardiovasc Pharmacol. 2011 Feb;57 (2) :166-73.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 2

• Isoform :

  Adenosine A2A receptor (A2AR)

• CAS Number :

  [90596-75-1]