Anticancer agent 146

• Description :

  Anticancer agent 146 (compound 1.19) is a necroptosis inducer. Anticancer agent 146 has anti-tumor efficacy in the mouse MDA-MB-231 xenograft model[1].

• UNSPSC :

  12352005

• Target :

  Necroptosis

• Type :

  Reference compound

• Related Pathways :

  Apoptosis

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/anticancer-agent-146.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C1=CC=C(N2CCNCC2)C=C1)C3=CC4=CC(Cl)=CC(Cl)=C4O3

• Molecular Formula :

  C19H16Cl2N2O2

• Molecular Weight :

  375.25

• References & Citations :

  [1]Schumacher TJ, et al. Synthesis and biological evaluation of benzofuran piperazine derivatives as potential anticancer agents. Bioorg Med Chem Lett. 2023 Sep 1;93:129425..

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [9007-83-4]