Anticancer agent 146

• UNSPSC Description:

  Anticancer agent 146 (compound 1.19) is a necroptosis inducer. Anticancer agent 146 has anti-tumor efficacy in the mouse MDA-MB-231 xenograft model[1].

• Target Antigen:

  Necroptosis

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Applications:

  Cancer-programmed cell death

• Field of Research:

  cancer

• Assay Protocol:

  https://www.medchemexpress.com/anticancer-agent-146.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=CC=C(N2CCNCC2)C=C1)C3=CC4=CC(Cl)=CC(Cl)=C4O3

• Molecular Weight:

  375.25

• References & Citations:

  [1]Schumacher TJ, et al. Synthesis and biological evaluation of benzofuran piperazine derivatives as potential anticancer agents. Bioorg Med Chem Lett. 2023 Sep 1;93:129425..

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  9007-83-4