Products for Research Use Only
RegisterLogin

YT 6-2

CAT: 0804-HY-169388Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-169388Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
YT 6-2 is the p62/SQSTM1 targeting, autophagy-targeting ligand (ATL) of AUTOTAC ATC-324 , which is an bivalent AR (Androgen Receptor) degrader. ATC-324 can reduce nuclear AR levels and downregulate target gene expression of AR and AR-v7, and also has a degradation effect on common AR mutants in PCa[1].
CAS Number
2409959-90-4
UNSPSC
12352005
Target
AUTACs
Type
Reference compound
Related Pathways
Autophagy; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/yt-6-2.html
Smiles
FC(C=C1)=CC=C1COC2=C(C=CC(OC[C@H](O)CNCCO)=C2)OCC3=CC=C(C=C3)F
Molecular Formula
C25H27F2NO5
Molecular Weight
459.48
References & Citations
[1]NOVEL P62 LIGAND COMPOUND, AND COMPOSITION CONTAINING SAME FOR PREVENTING, ALLEVIATING, OR TREATING PROTEIN ABNORMALITY DISORDERS. WO2020022783.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-106303-01YT 146
HY-161737-01YT-8-8
HY-110085-012,2′-Dihydroxy-6,6′-dinaphthyl disulfide
HY-W077671-012,2,6-Trimethylcyclohexanone
HY-W654295Norethindrone-2,2,4,6,6,10-d6
HY-N17282-Ethyl-2,6,6-trimethylpiperidin-4-one
HY-132403S-014- (6-Nitro-3-pyridinyl) -piperazine-2,2,6,6-d4
HY-W012126-012,6-Dichlorodiphenylamine
HY-144178HIF-2α-IN-6
HY-153455TRPC3/6-IN-2

Alternative Products

CatalogName
7322500-500MLGOAT SERUM UNFILTERED 500 ML
7323100-100MLGUINEA PIG SERUM UNFILTERED 100 ML
7323400-100MLHORSE SERUM UNFILTERED 100 ML
7323100-1LTRGUINEA PIG SERUM UNFILTERED 1 LTR
7322500-100MLGOAT SERUM UNFILTERED 100 ML
7323100-50MLGUINEA PIG SERUM UNFILTERED 50 ML
7322100-100MLDONKEY SERUM UNFILTERED 100 ML
7323100-500MLGUINEA PIG SERUM UNFILTERED 500 ML
7322100-1LTRDONKEY SERUM UNFILTERED 1 LTR
7322500-1LTRGOAT SERUM UNFILTERED 1 LTR

Popular Products