BAY-549

CAT: 0804-HY-10319-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-10319-01Size:5 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BAY-549 (Azaindole 1), a chemical probe, is an orally active and ATP-competitive ROCK inhibitor with IC50s of 0.6 and 1.1 nM for human ROCK-1 and ROCK-2, respectively[1].
CAS Number
[867017-68-3]
Product Name Alternative
ROCK-IN-2; Azaindole 1; TC-S 7001
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
ROCK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton; Stem Cell/Wnt; TGF-beta/Smad
Applications
COVID-19-anti-virus
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/bay-549.html
Purity
99.46
Solubility
DMSO : 33.33 mg/mL (ultrasonic)
Smiles
NC1=NC(Cl)=CC(NC2=CC(F)=C(OC3=C4C(NC=C4C)=NC=C3)C(F)=C2)=N1
Molecular Formula
C18H13ClF2N6O
Molecular Weight
402.79
Precautions
H302, H315, H319, H335
References & Citations
[1]Kast R, et al. Cardiovascular effects of a novel potent and highly selective azaindole-based inhibitor of Rho-kinase. Br J Pharmacol. 2007 Dec;152 (7) :1070-80. Epub 2007 Oct 15.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ROCK1; ROCK2

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