BAY-179

• UNSPSC Description:

  BAY-179 is a potent, selective, and species cross-reactive complex I inhibitor (IC50=79 µM)[1].

• Target Antigen:

  Mitochondrial Metabolism

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/bay-179.html

• Solubility:

  DMSO : 62.5 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  C12=C(OC(C3=CSC(C4CCN(CC5=NC6=C(C=CC=N6)N5)CC4)=N3)=C2)C=CC=C1

• Molecular Weight:

  415.51

• References & Citations:

  [1]Mowat J, et al. Identification of the Highly Active, Species Cross-Reactive Complex I Inhibitor BAY-179. ACS Med Chem Lett. 2022;13(3):348-357. Published 2022 Feb 18.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2764880-87-5