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(+) -BAY-7081

CAT: 0804-HY-152106A-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-152106A-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(+) -BAY-7081 is an optical isomer of BAY-7081. BAY-7081 is a potent, selective, orally active and soluble cyanopyridone-based PDE9A inhibitor with an IC50 of 15 nM[1].
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Purity
99.21
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
N#CC1=C(N(CC2)CCC32CC3)C4=C(NC1=O)C(CCC)CNC4.Cl
Molecular Formula
C19H27ClN4O
Molecular Weight
362.90
References & Citations
[1]Meibom D, et al. BAY-7081: A Potent, Selective, and Orally Bioavailable Cyanopyridone-Based PDE9A Inhibitor. J Med Chem. 2022 Dec 22;65 (24) :16420-16431.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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