Products for Research Use Only
RegisterLogin

BAY-9835

CAT: 0804-HY-162284-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-162284-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
BAY-9835, a chemical probe, is an orally active ADAMTS7 and ADAMTS12 antagonist with IC50s of 6 nM and 30 nM, respectively. BAY-9835 exhibits inhibitory potencies vs mouse (mIC50 = 8 nM) and rat (rIC50 = 27 nM) ADAMTS7 enzymes. BAY-9835 is very selective against a range of off-targets and metalloproteases. BAY-9835 can be used for the study of atherogenesis[1].
CAS Number
3032487-31-0
UNSPSC
12352005
Target
ADAMTS
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/bay-9835.html
Purity
99.46
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=C(F)C(F)=C1C2=CC=C(C(F)(F)F)C=C2)NC[C@@](C(N3)=O)(C4=CC=NN4C)NC3=O
Molecular Formula
C22H16F5N5O3
Molecular Weight
493.39
References & Citations
[1]Daniel Meibom, et al. BAY-9835: Discovery of the First Orally Bioavailable ADAMTS7 Inhibitor. J Med Chem. 2024 Feb 22;67 (4) :2907-2940.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-P1160-01Bay 55-9837
HY-P1160ABay 55-9837 (TFA)
HY-130248-01BAY-899
HY-145939-01BAY-888
HY-103020-01BAY-1816032
HY-122312-01BAY-8002
HY-112083-01BAY-3827
HY-156701BAY-1128688
HY-152106B-01(±) -BAY-7081
HY-152106A-01(+) -BAY-7081

Alternative Products

CatalogName
T202655-01BAY-9835
CON3245Hanna Conductivity Probe for 9835
MBS131507BAY-1217389 BAY 1217389? BAY 1217389?
A4210-25Bay 11-7821 (BAY 11-7082)
M36493-01BAY 2965501
M36091-01BAY-4931
M23710-01BAY-1251152
M22446-01BAY-985
BA3948-1BAY-8400
BA8899-25BAY-826

Popular Products