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BAY-1128688

CAT: 0804-HY-156701Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-156701Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BAY-1128688 is a potent, orally active and selective AKR1C3 inhibitor with IC50 [1].
CAS Number
1428988-21-9
UNSPSC
12352005
Target
Aldose Reductase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Endocrinology
Smiles
C[C@@]12[C@](CC=C2C3=CN=CC(F)=C3)([H])[C@@]4([H])[C@@](CC1)([H])C5=CC=C(C(N(C)CCC(O)=O)=O)C=C5CC4
Molecular Formula
C28H31FN2O3
Molecular Weight
462.56
References & Citations
[1]Hilpert J, et al. Hepatotoxicity of AKR1C3 Inhibitor BAY1128688: Findings from an Early Terminated Phase IIa Trial for the Treatment of Endometriosis. Drugs R D. 2023 Sep;23 (3) :221-237.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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