CDK8-IN-11
CAT:
804-HY-151463-03
Size:
10 mM / 1 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
CDK8-IN-11
- CAS Number: 2839338-28-0
- UNSPSC Description: CDK8-IN-11 is a potent and selective CDK8 inhibitor with an IC50 value of 46 nM. CDK8-IN-11 inhibits WNT/β-catenin signaling pathway. CDK8-IN-11 can be used in the research of colon cancer[1].
- Target Antigen: CDK; β-catenin
- Type: Reference compound
- Related Pathways: Cell Cycle/DNA Damage;Stem Cell/Wnt
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/cdk8-in-11.html
- Solubility: DMSO : 250 mg/mL (ultrasonic)
- Smiles: O=C(NC1=CC=CC(C(F)(F)F)=C1)NC2=CC=C(OC3=CC=C(N)N=C3)C=C2
- Molecular Weight: 388.34
- References & Citations: [1]Yao Yao Yan, et al. Design and Synthesis of a 2-Amino-pyridine Derivative as a Potent CDK8 Inhibitor for Anti-colorectal Cancer Therapy. J Med Chem. 2022 Sep 20.
- Shipping Conditions: Blue Ice
- Clinical Information: No Development Reported