CDK8-IN-18

• Description:

  CDK8-IN-18 (compound BRD-2299) is a potent inhibitor of CDK8, with the IC50 of 43 μM. CDK8-IN-18 plays an important role in cancer research[1].

• UNSPSC:

  12352005

• Target:

  CDK

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Smiles:

  N#CC1=C(C2=CN=CC=C2)C(CC)=C(CCC)N=C1N

• Molecular Formula:

  C16H18N4

• Molecular Weight:

  266.34

• References & Citations:

  [1]The Broad Institute, Inc., et al. Use of CDK8 inhibitors to treat diseases of inflammation and autoimmunity. World Intellectual Property Organization, WO2018027082 A1 2018-02-08

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  CDK8

• CAS Number:

  642002-74-2