CDK8-IN-1

CAT: 0804-HY-103492-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-103492-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CDK8-IN-1 is a potent and selective CDK8 inhibitor with an IC50 of 3 nM.
CAS Number
[1629633-48-2]
UNSPSC
12352005
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/CDK8-IN-1.html
Purity
99.77
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
NC(C1=C(C(F)(F)F)C(C2=CC=NC=C2)=CN1)=O
Molecular Formula
C11H8F3N3O
Molecular Weight
255.20
References & Citations
[1]Han X, et al. Discovery of potent and selective CDK8 inhibitors through FBDD approach. Bioorg Med Chem Lett. 2017 Sep 15;27 (18) :4488-4492.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK8

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