PROTAC eEF2K degrader-1

PROTAC eEF2K degrader-1

• CAS Number: 2458170-54-0
• UNSPSC Description: PROTAC eEF2K degrader-1 (Compound 11l) is an eEF2K-Targeting PROTAC small molecule that induces apoptosis in MDA-MB-231 cells. PROTAC eEF2K degrader-1 mediates eEF2K degradation[1].
• Target Antigen: Apoptosis; CaMK; PROTACs
• Type: Reference compound
• Related Pathways: Apoptosis;Neuronal Signaling;PROTAC
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/protac-eef2k-degrader-1.html
• Solubility: DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C)
• Smiles: CCN1C(N(C(C2=C1N=C(C(C(N)=O)=C2)N)=O)CC(NCCOCCNC(COC3=CC=CC4=C3C(N(C4=O)C5CCC(NC5=O)=O)=O)=O)=O)=O
• Molecular Weight: 707.65
• References & Citations: [1]Yao Liu, et al. Designing an eEF2K-Targeting PROTAC small molecule that induces apoptosis in MDA-MB-231 cells. Eur J Med Chem. 2020 Oct 15;204:112505.
• Shipping Conditions: Blue Ice
• Clinical Information: No Development Reported