MLT-985

• UNSPSC Description:

  MLT-985 is a highly selective allosteric MALT1 inhibitor with an IC50 value of 3 nM.

• Target Antigen:

  MALT1

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease;NF-κB

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/mlt-985.html

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  CO[C@H](C1=C(NC(NC2=CN=C(N3N=CC=N3)C(Cl)=C2)=O)C=NC4=CC(Cl)=NN14)C

• Molecular Weight:

  448.27

• References & Citations:

  [1]Quancard J, et al. Optimization of the In Vivo Potency of Pyrazolopyrimidine MALT1 Protease Inhibitors by Reducing Metabolism and Increasing Potency in Whole Blood. J Med Chem. 2020 Dec 10;63(23):14594-14608.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1832576-25-6