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(Rac) -BAY-985

CAT: 0804-HY-133117ASize: 1 EachDry Ice: NoHazardous: No
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Description
(Rac) -BAY-985 (Compound Example 100.01) is a potent, ATP-competitive and selective TBK1 inhibitor with an IC50 of 1.5 nM. Antitumor efficacy[1].
CAS Number
2101925-20-4
UNSPSC
12352005
Target
IKK
Type
Reference compound
Related Pathways
NF-κB
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rac-bay-985.html
Solubility
10 mM in DMSO
Smiles
O=C(N1CCN(C(C2=CC(NC3=NC4=CC=C(C5=NC=NC(N(C)C)=C5)C=C4N3)=NC=C2)C)CC1)CC(F)(F)F
Molecular Formula
C27H30F3N9O
Molecular Weight
553.58
References & Citations
[1]Volker Schulze, et al. Heteroarylbenzimidazole compounds. WO2017102091A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TBK1

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