RegisterLogin

MLT-231

CAT: 0804-HY-131902-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-131902-01Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
MLT-231 is a potent, highly selective allosteric MALT1 Inhibitor with an IC50 of 9 nM. MLT-231 specifically prevents endogenous BCL10 cleavage with IC50 of 160 nM. MLT-231 shows antitumor activity in an ABC-DLBCL type xenograft model in mouse[1].
CAS Number
[2682102-10-7]
UNSPSC
12352005
Target
MALT1
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mlt-231.html
Purity
99.55
Solubility
DMSO : 110 mg/mL (ultrasonic)
Smiles
O=C(NC1=C(N2[C@@H](C)COC[C@@H]2C)N3C(N=C1)=CC(Cl)=N3)NC4=CC=NC(C(F)(F)F)=C4
Molecular Formula
C19H19ClF3N7O2
Molecular Weight
469.85
References & Citations
[1]Pissot Soldermann C, et al. Discovery of Potent, Highly Selective, and In Vivo Efficacious, Allosteric MALT1 Inhibitors by Iterative Scaffold Morphing [published online ahead of print, 2020 Nov 30]. J Med Chem. 2020;10.1021/acs.jmedchem.0c01245.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-134820-01MLT-943
HY-124587-01MLT-747
HY-142648-01MLT-985
HY-115466-01MLT-748
HY-142648A(R) -MLT-985
HY-13945-01NVP 231
HY-103320-01Calhex 231
HY-148827GEM-231
HY-124611-01JG-231
HY-179657PROTAC MLT Degrader 1

Alternative Products

CatalogName
T38096-01MLT-231
MBS3843401-01MLT-747
T39271MLT-985
C53MR1038-50Maltose, MLT
C13762-01MLT-748
BA7967-5.1MLT-943

Popular Products