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Nrf2-IN-1

CAT: 0804-HY-101025-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-101025-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Nrf2-IN-1 is an inhibitor of nuclear factor-erythroid 2-related factor 2 (Nrf2) . Nrf2-IN-1 is developed for the research of acute myeloid leukemia (AML) [1].
CAS Number
1610022-76-8
UNSPSC
12352005
Target
Keap1-Nrf2
Type
Reference compound
Related Pathways
NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nrf2-in-1.html
Purity
99.88
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(NO)C1=CC(C2=CC=C(Cl)C=C2)=NN1CC3=CC=C(C(C)(C)C)C=C3
Molecular Formula
C21H22ClN3O2
Molecular Weight
383.87
References & Citations
[1]Zhang J, et al. Discovery of a novel Nrf2 inhibitor that induces apoptosis of human acute myeloid leukemia cells. Oncotarget. 2017 Jan 31;8 (5) :7625-7636.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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BA8615-1Nrf2-IN-1
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T11752-01Keap1-Nrf2-IN-1
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A12561-100Nrf2-IN-1 100mg
A12561-10Nrf2-IN-1 10mg
A12561-5Nrf2-IN-1 5mg
A12561-500Nrf2-IN-1 500mg
A12561-50Nrf2-IN-1 50mg
A12561-25Nrf2-IN-1 25mg

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