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Axl (AB2294) Rabbit mAb

CAT: 0808-M3595-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0808-M3595-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6) . This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
Synonyms
AXL, UFO, Tyrosine-protein kinase receptor UFO, AXL oncogene
Gene Name
AXL UFO
Gene ID
558
Swiss Prot
P30530
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein (or fragment) . This information is considered to be commercially sensitive.
Clonality
Monoclonal
Source
Monoclonal, Rabbit, IgG
Applications
WB, IHC, IF, IP, ELISA
Purification
The antibody was purified by protein A affinity chromatography.
Dilution
WB, 1:2000-1:10000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5μg-4μg antibody for 200μg-400μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Modification
Unmodified
Storage Conditions
Store at-20°C. Avoid freeze / thaw cycles.
Specificity
This antibody detects endogenous levels of Axl protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.
Protein Name
Axl