PF-9184

CAT: 0804-HY-19622-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-19622-01Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
PF-9184 is a potent and highly selective inhibitor of human microsomal prostaglandin E synthase-1 (mPGES-1), with an IC50 of 16.5 nM. PF-9184 inhibits IL-1β-induced PGE2 synthesis in vitro[1].
CAS Number
[1221971-47-6]
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
PGE synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/pf-9184.html
Purity
98.10
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(C1=C(O)C2=CC=CC=C2S(N1)(=O)=O)NC3=CC=C(C4=CC=C(Cl)C(Cl)=C4)C=C3
Molecular Formula
C21H14Cl2N2O4S
Molecular Weight
461.32
Precautions
H315, H319, H335
References & Citations
[1]Gabriel M, et, al. Distinction of microsomal prostaglandin E synthase-1 (mPGES-1) inhibition from cyclooxygenase-2 inhibition in cells using a novel, selective mPGES-1 inhibitor. Biochem Pharmacol. 2010 May 15; 79 (10) : 1445-54.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-16387PF 00337210
HY-121775-01PF-00217830
HY-11045PF-03654746
HY-120811PF-04701475
HY-120464PF-05212377
HY-19550PF-06442609
HY-107591BPF-184
HY-117257PF-0713
HY-118978PF-00277343
HY-P990649-01PF-5212374

Alternative Products

CatalogName
M10842-01PF-9184
462318-01PF 9184
NBP3-26975HMouse Monoclonal MYH7 Antibody (MYH7/9184) [HRP]
NBP3-26827-100ugMouse Monoclonal MYH7 Antibody (MYH7/9184)
NBP3-26975PEMouse Monoclonal MYH7 Antibody (MYH7/9184) [PE]
MBS579460PF-03084014 (PF-3084014)
TL314412BUB3 Human shRNA Plasmid Kit (Locus ID 9184)
NBP3-26975CMouse Monoclonal MYH7 Antibody (MYH7/9184) [DyLight 650]
NBP3-26975IRMouse Monoclonal MYH7 Antibody (MYH7/9184) [DyLight 755]
NBP3-26975BMouse Monoclonal MYH7 Antibody (MYH7/9184) [Biotin]

Popular Products