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Curcumin 5-8

CAT: 0804-HY-148598-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-148598-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Curcumin 5-8 (CUR5-8) is a potent and orally active naturally active curcumin (CUR) analog. Curcumin 5-8 inhibits lipid droplet formation. Curcumin 5-8 increases autophagy and inhibits Apoptosis. Curcumin 5-8 improves insulin resistance and insulin sensitivity[1].
CAS Number
890984-26-6
Product Name Alternative
CUR5-8
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Autophagy
Type
Natural Products
Related Pathways
Apoptosis; Autophagy
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/curcumin-5-8.html
Concentration
10mM
Purity
98.58
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CC(NC(C(C)C)=O)=CC=C1)/C=C/C2=CC=C(C(OC)=C2)O
Molecular Formula
C20H21NO4
Molecular Weight
339.39
Precautions
H302, H315, H319, H335
References & Citations
[1]Lee ES, et al. Curcumin analog CUR5-8 ameliorates nonalcoholic fatty liver disease in mice with high-fat diet-induced obesity. Metabolism. 2020 Feb;103:154015.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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