Difluorinated Curcumin

• UNSPSC Description:

  Difluorinated Curcumin (3,4-Difluorobenzylidene curcumin) is a fluorinated curcumin analog with high bioavailability and anticancer activity. Difluorinated Curcumin inhibits the self-renewal ability of tumor stem/stem-like cells, clonogenicity, invasiveness and angiogenesis of tumor cells. Difluorinated Curcumin also increases cell sensitivity to chemotherapy[1].

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Applications:

  Cancer-programmed cell death

• Field of Research:

  cancer

• Assay Protocol:

  https://www.medchemexpress.com/difluorinated-curcumin.html

• Solubility:

  10 mM in DMSO

• Smiles:

  FC(C=C1/C=C(C(/C=C/C2=CC(OC)=C(C=C2)O)=O)/C(/C=C/C3=CC(OC)=C(C=C3)O)=O)=C(C=C1)F

• Molecular Weight:

  492.47

• References & Citations:

  [1]Momtazi AA, et al. Difluorinated Curcumin: A Promising Curcumin Analogue with Improved Anti-Tumor Activity and Pharmacokinetic Profile. Curr Pharm Des. 2016;22(28):4386-97.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1170354-22-9